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The additional GIP component can lead to more significant metabolic changes and weight loss, which may result in a more pronounced adjustment period and temporary fatigue for some individuals

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Researchers remark that AIDS, with associated renal abnormalities or hypoalbuminemia, may increase the risk for elevated free fractions of phenytoin (Tbler et al., 1990)

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Currently, only three medications are FDA-approved to treat AUD

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10.1083/jcb.201804161 32

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That feature makes it uniquely useful when drug development generates improvements that are intertwined with the original invention and cannot be claimed effectively in a standalone application

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