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However, the physiological substrates of OCTN1 are still matter of discussion (Pochini et al., 2019 and Table 1)

Abrupt discontinuation is generally discouraged, as gradually tapering the dose can help minimize rebound appetite and reduce blood sugar instability

Moderate alcohol is not contraindicated, but semaglutide can amplify alcohol's effects on blood sugar and on the gut

While semaglutide is safe for most individuals, some may experience side effects, including: Nausea and vomiting Diarrhea Constipation Stomach pain Reduced appetite These side effects are generally mild and tend to decrease over time as the body adjusts to the medication

10.3390/toxins2040572 Toxins 117 MitchellN.BowersE.HurburghC.WuF

Common Pitfalls and How to Avoid Them (Our Team's Advice) We've seen it all