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Subacute Toxicity Maximum no-effect dose in rats: 450 mg/kg, cecal enlargement, increased K+ and Cl- in urine

Under AGEs-induced HRECs, miR-125b-5p suppresses P53-mediated ferroptosis by restoring glutathione peroxidase 4 (GPX4) activity and blocking lipid peroxidation, thereby preserving blood-retina barrier (BRB) integrity (64)

[17] In humans, glutathione synthetase functions in a similar manner

SARS-CoV-2 virus NSP14 Impairs NRF2/HMOX1 activation by targeting Sirtuin 1

[00034] "Odor" as used herein refers to any pungent smell or stench