Potential synergies Combining FOXO4-DRI with regenerative therapies: e.g., stem cell therapies, hormone replacement, peptides promoting regeneration (such as GHK-Cu, MOTS-c) clearing senescent cells may clear the field for regeneration
The general principle described in clinical teaching is to establish a baseline, recheck IGF-1 after the early weeks of any protocol, keep it within an age-appropriate reference range rather than pushing it into supraphysiologic territory, and monitor fasting glucose in at-risk patients
Ro or Hims are more streamlined for that
oral semaglutide and other formulations may be suitable alternatives
doi: 10.1007/s00403-024-03020-1 18 ZhaoBZhangMTangJZouDLiuFShiQet al
Reviewed by Meghan Salamon, MS, RDN, LDN, CPT, Contributor Looking to lose weight