5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small molecule that inhibits NNMT (nicotinamide N-methyltransferase), an enzyme that becomes overactive in metabolically aging tissue
However, for B12, if any part of that complex digestive process is compromised especially the intrinsic factor or the absorption sites in the intestine then a significant portion of the B12 from a tablet might never reach your bloodstream
From there, vitamin B12 combines with a protein called intrinsic factor so that it can be absorbed further down in the small intestine
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High doses of B12 may worsen the disease and cause irreversible damage to the optic nerve
Even those who occasionally eat animal products may not consume enough to meet daily needs, particularly if they rely heavily on processed or plant-based convenience foods