Anaerobe 14(1):4348
Treatment of B6 mice with the GLS1 inhibitor BPTES significantly reduced histological scores in the spinal cord of affected animals, lowered the number of CD4 + T cells, IL-17A and IFN-producing CD4 + T cells in the spinal cord, substantially decreased clinical scores and weight loss, and ameliorated experimental autoimmune encephalomyelitis (47)
Side effects : May include dizziness, nausea, menstrual changes, and rare potassium issues
Participants could be discontinued for serious adverse events, withdrawal of consent, or clinician judgment of unacceptable risk
A "2 mg" vial from one pharmacy may deliver a different actual copper load than a "2 mg" vial from another
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