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Synthesis of Amodiaquine Quinoneimine (AQ-QI) and Desethylamodiaquine Quinoneimine (DEAQ-QI) Synthesis of AQ-QI and DEAQ-QI was adapted from a method published previously, with a few modifications ( in vacuo and then applied to a silica-60 column to remove the tracing AQ or DEAQ

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The clinical and laboratory characteristics of the study participants are shown in Table 1

This inflammatory cascade, characterized by the release of pro-inflammatory cytokines such as tumor necrosis factor- (TNF-) and interleukin-6 (IL-6), drives hepatocellular injury and liver failure [18,19]

(Source 14) Bottom line: Avoid synthetic food dyes and choose dye-free or naturally dyed products instead