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It is important in the heart in regulating rhythm, and it has recently been discovered to play an important role in the alpha-cells of the pancreas with the release of glucagon.[ref] Genetic variants in KCNH2 have links to a decrease in glucagon production
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Therefore, regulating tumour progression hinges on maintaining ROS below the critical threshold that supports oncogene dependence [23], on the basis of which targeted regulation of SOD activity is regarded as a potential strategy in cancer treatment [24]
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Whole blood was centrifuged at 3,000 g for 10 minutes to isolate plasma
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