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There is an immense effort to reveal the underlying causes of TDP-43 pathology and the downstream cellular events that are perturbed in diseased neurons
W.ChenY
Genes associated with PD, such as PTEN-induced kinase 1 (PINK1), Parkin, DJ-1, LRRK2, and ATP13A2, are directly or indirectly involved in maintaining mitochondrial integrity and function
Cell Host MicrobeBacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity
Vrahatis et al., 2023)
These findings support the use of SGLT2 inhibitors as foundational therapy across the HF spectrum, with early initiation favored when clinically appropriate [13]
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