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Well, one theory is that not all GLP-1 RAs are created equal

Benefits include: Average weight loss of up to 15 to 25% in clinical studies Improved portion control and satiety Support for balancing blood sugar and metabolic health GLP-1/GIP Dual Agonists These advanced options activate both GLP-1 and GIP (gastric inhibitory polypeptide) receptors for enhanced appetite control, glucose balance, and fat metabolism

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Weight, measurements, appetite levels, side effects, energy, sleep quality, and food intake should all be tracked from day one

In SURMOUNT-1, 72 weeks of tirzepatide induced mean WL of 1622.5% in people without diabetes compared to 2.4% with placebo, with no sign of the weight plateauing, suggesting that there may be further WL with long-term use [46]