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CoQ 10 oxidoreductases in the regulation of ferroptosis (1) FSP1 in the regulation of ferroptosis FSP1 as a therapeutic target in cancer FSP1 (formerly AIFM2) was first identified as a ferroptosis regulator among CoQ 10 oxidoreductases through independent unbiased genetic screens conducted by the Conrad and Olzmann groups under conditions of GPX4 inhibition 16,17
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With this in mind, we explored the GEP44-mediated internalization of Y2-R and internalization and recruitment of -arrestin-2 at GLP-1R (Fig
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