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In endometrial stromal cells (ESC), TNF-induced activation of the estrogen receptor ER leads to heightened ERK activation (53)
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That is a useful scientific question, but it does not describe most patients in the real world
Interestingly, SGLT-2 inhibitors were the only drugs among vasodilators associated with significantly higher odds of OH
For comparison, the improvement in glycemic control following bariatric surgery is of the same order, with a decrease in A1c varying between 1.8 and 3.5%
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