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Neither compound should be understood as a proven anti-aging or general fat-loss agent, and both are prohibited in sport by the World Anti-Doping Agency (WADA)

10.1039/d4fo01059k 102 TolhurstG.HeffronH.LamY

Fletcher Family Medical Center (Subsema, Compounded Sublingual Semaglutide Product) , Report #7518, NAD/CARU Case Reports (November 2025 )

The side effect profiles for semaglutide and tirzepatide are better characterized because both medications have been on the market longer

A doctor may have instructed them to take it on an empty stomach and wait a certain length of time before eating or drinking anything except water

When the drug lowers your hunger, it does the same for your thirst as well