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The activity of IF 1 protects cells during periods of ischemia where O 2 levels fall leading to a reduced proton gradient
Hasanuzzaman M, Bhuyan MH, Anee TI, Parvin K, Nahar K, Mahmud JA, Fujita M (2019) Regulation of ascorbate-glutathione pathway in mitigating oxidative damage in plants under abiotic stress
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The phosphocholine head group in phospholipids of normal healthy cell membranes is not accessible but, when cells are damaged and die, enhanced availability of lysophosphatidylcholine and disruption of the lipid bilayer expose phosphocholine residues to which CRP avidly binds (99)
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Together, these findings highlight that viral-induced mitochondrial stress engages a network of innate immune sensors-including cGAS and TLR9, interplay determines whether antiviral defense or pathological inflammation predominates
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