This study was supported by The National Natural Science Foundation of China (31300978)
Male mice exposed to CMS for 2 weeks showed increased pathogenic bacteria including Acinetobacter, Proteus , and Enterococcus (Tyagi et al., 2025)
TB-500 binds monomeric G-actin through the central LKKTETQ motif, sequestering actin monomers and modulating the cytoplasmic pool available for filament elongation in cell-based assays
ascites and encephalopathy) and, if required, can support patients by ensuring diuretic therapy is optimised, infection prophylaxis is initiated and salt is restricted through dietary adjustments
A 50 mg vial mixed with 3.0 mL of bacteriostatic water gives about 16.7 mg/mL, and the example subcutaneous range is 2.5 to 5 mg per day
Products are stored in industrial-grade freezers prior to shipment to maintain stability and purity