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As expected, GLP-1R agonism resulted in a reduced intake of both control liquid and ethanol diets, and a corresponding reduction of body weight in both the control and ethanol groups (Supplementary Fig
doi:10.1056/NEJMoa2204601 Haddad F, Dokmak G, Bader M, et al
Patients included in PIONEER 5 and PIONEER 6 were living with moderate renal impairment (eGFR 30 to 59 mL/min/1.73 m 2 ), and cardiovascular disease, respectively
Tirzepatide is a dual agonist that activates the GLP-1 and GIP receptors
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