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Retrieved May 27, 2025, from Brooks, M
After initial repletion, a maintenance dose is given, often 1,000 mcg intramuscularly every month or every 2 to 3 months, to prevent recurrence of deficiency
NNMT activity returns to baseline within 4872 hours, and mitochondrial NAD+ levels normalize accordingly
See these diagrams: Source: Clinical Procedures for Safer Patient Care by Doyle & McCutcheon
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Body Composition Changes: More significant changes, such as a reduction in body fat or noticeable weight loss, typically occur over a period of 48 weeks
