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More than 5% of adults using Mounjaro in studies reported constipation as a side effect

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The sensation may be so unpleasant that people will purposely avoid certain foods

Practical implication: if manual injection technique, needle anxiety, or ease of self-administration is important, a pen/autoinjector (Tirzee) may be preferred even if it costs more

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Eating smaller, more frequent meals and avoiding high-fat foods may help manage gastrointestinal symptoms