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Applying degraded GHK-Cu delivers free copper ions that can generate reactive oxygen species on skin, potentially causing irritation or hyperpigmentation rather than collagen stimulation

The original characterization by the Sikiri group framed the larger parent protein in human gastric juice as a protective factor for the gastrointestinal mucosa, with body protection compound (BPC) referring to that broader protective role

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In laboratory settings, GHK-Cu may be used to investigate: All uses are limited to research settings only

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