The two models generate fundamentally different return profiles, exposure periods, and risk distributions
le Roux
shortening the time horizon of the analyses to 35, 20 and 10 years (for which it should be noted that some patients were still alive at the end of the modelling period and, therefore, not all costs and consequences were captured)
So while this comparison raised questions about how the treatment stacks up against competitors, it doesnt necessarily affect its chances of approval
Chosy EJ, Edland S, Launer L, White LR
High-risk patients are flagged before the appointment, allowing clinicians to prepare counter-arguments or alternative treatments