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Exposure of the liver to xenobiotic substances means the body prepares itself by increasing detoxification enzymes, i.e., cytochrome P-450 mixed-function oxidase

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Plasma levels decline with age, which is part of why it became a research target for skin, hair, and wound healing

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Positions it at the intersection of aging research, metabolic disease, and mitochondrial biology, which are high-priority research areas

Glutathione helps by reducing oxidative stress as well as inflammation, both contributors to liver disease, including nonalcoholic fatty liver disease