early life stress or chronic drug exposure [15,16,17], may lead to redox dysfunction and chronic oxidative stress, strongly linked to the pathophysiology of schizophrenia [18,19,20,21,22]
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Tissue homogenates from chronically rejected human renal allografts demonstrated decreased activity of MnSOD and increased expression of MnSOD protein (MacMillan-Crow et al., 1996)
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