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Conclusions Although studies have demonstrated the efficacy of GLP-1 receptor agonists (GLP-1 RAs) and SGLT-2 inhibitors in improving conditions associated with new-onset diabetes mellitus (DM) and chronic kidney disease (CKD), there is a scarcity of data regarding their use after liver transplantation

The peptide sequence and its fatty acid conjugation create a half-life of approximately six days, which enables once-weekly dosing in clinical protocols

Principally used in the management of type 2 diabetes mellitus (T2DM) and obesity, recent work posits a broader role of the peptide in modulating numerous physiologic pathways [11, 12]