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108 Further research has shown that BACH1 inhibits the Nrf2 pathway by binding to Nrf2, and promotes the increase of labile iron in PDAC cells, leading to ferroptosis
They are potent biologic therapeutics with 35 listed adverse side effects, and caution warnings for people with existing conditions such as pancreatitis, suicide ideation and thyroid cancer
Clinic Rev Allerg Immunol 61 , 403423 (2021)
doi:10.1016/j.mam.2008.05.005 Ma, X., Jiang, Y., He, Y., Bao, R., Chen, Y., & Zhou, C