Zepbound (tirzepatide) slows gastric emptying, causing food to remain in the stomach longer than usual
By the end of the first year, 40,262 people had discontinued the medication entirely
Causes of deficiency can include an insufficient diet of animal products, gastrointestinal problems that affect absorption, and certain autoimmune medical conditions
The 2025 data is genuinely encouraging but still early much of it is retrospective or database-based, not randomized trials in RA
Conclusions This open-label, single-center pilot study suggests that GLP-1-RAs are an effective and safe treatment option for achieving significant weight loss with a favorable effect on headache, leading to reduced acetazolamide dosage in pwIIH
If you notice any of those, pause and call your provider