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During times of oxidative stress, the GST genes are upregulated

Reported benefits (per available research): Studied in rat full-thickness wound models for accelerating skin repair, with one study reporting reepithelialization increased by up to 61% over controls by day 7, along with greater wound contraction and collagen deposition (Malinda et al., animal study, 1999) Studied in rodent models of ischemic myocardial injury for reducing post-infarct scarring and supporting cardiac tissue repair

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Transcriptional up-regulation of gamma-glutamylcysteine synthetase gene expression in melphalan-resistant human prostate carcinoma cells

Peripheral vascular thrombosis has also occurred