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Higher GABA activity in the brainstem can reduce the sensitivity of the area postrema to nausea triggers, effectively raising the threshold for how much GLP-1 stimulation is needed before nausea occurs
This is a huge plus for anyone who experiences intense cravings and has a problem with overeating
Journal of Clinical Endocrinology and Metabolism: Body Composition Changes with GLP-1 Receptor Agonists - Analysis of lean mass loss during weight loss on GLP-1 therapy
The benzyl alcohol in bacteriostatic water provides this property
which explains how Medicaid drug coverage works and why weight loss meds are treated differently from most prescriptions
Some users sweat more during moderate exertion that previously did not cause sweating
