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Additionally, the PPP provides erythrose-4-phosphate, a precursor for the synthesis of aromatic amino acids through the shikimate pathway

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192 Studies have shown that Fusobacterium nucleatum promotes the occurrence and development of UC by destroying the normal intestinal structure, downregulating the level of tight junction proteins, promoting the apoptosis of intestinal epithelial cells, increasing the expression of inflammatory cytokines, and disrupting the balance of the intestinal microbiota

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These are reported in Supplementary Table 1 and the interactions of the peptide N-termini with the TMD are shown in Fig