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doi: 10.3389/fimmu.2022.919681 60 HuppertJCloshenDCroxfordAWhiteRKuligPPietrowskiEet al

Diabetes causes inhibition of glucose-6-phosphate dehydrogenase via activation of PKA, which contributes to oxidative stress in rat kidney cortex

GLP-1 agonists are synthetic analogues of the incretin hormone GLP-1, engineered to resist enzymatic breakdown by DPP-4 and prolong therapeutic activity

This led to an explosion in demand and cost for the drugs

Weight loss can normalize hormonal profiles, including increased testosterone levels in men with obesity and improved sex hormone binding globulin levels in women

Missed cholelithiasis may be complicated with deleterious consequences in patients with T2D