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Dosage: 200-300 mcg, 1-3 times daily via subcutaneous injection

The yeast produces metabolites (monacolins) that are naturally-occurring HMG-CoA reductase inhibitors (one of these, monacolin K, is chemically identical to lovastatin)

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5 A recent meta-analysis of 764 RCTs including 421,346 people with type 2 diabetes found that both medicine classes reduced: 6 All-cause mortality Cardiovascular mortality Non-fatal myocardial infarction Kidney failure The mechanism by which these medicines reduce adverse cardiovascular outcomes remains uncertain

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