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Injectable GLP-1 receptor agonists such as semaglutide (Wegovy) have demonstrated strong clinical efficacy, but long-term adherence challenges, injection fatigue, and access limitations continue to shape unmet medical needs

The control group used three other medication options: phentermine and topiramate, bupropion and naltrexone, or dulaglutide

Study authors not specified Clinical, Cosmetic and Investigational Dermatology

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GLP-1R is highly expressed in pancreatic cells, providing a clear pathway to directly promote insulin secretion