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In phase 2 trials, retatrutide achieved approximately 1718% weight loss in individuals with obesity without T2DM, surpassing most available pharmacotherapies 1,19

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BPC-157 is thought to promote healing partly by stimulating the formation of new blood vessels and upregulating growth-related pathways (including nitric oxide and VEGF-related signaling)

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In the context of triple-negative immunotherapy for breast cancer, the combination of pyroptosis induction with immune checkpoint inhibitors has significant synergistic potential [62]

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