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Ultimately, targeting the STAT3/V-ATPase pathway not only disrupts the survival mechanisms of detached tumor cells but also enhances anti-tumor immunity by promoting MDSC apoptosis, making it a promising strategy for preventing cancer metastasis and improving the therapeutic success of immunotherapy
Plates were imaged using a CellInsight CX5 HCS platform (Thermo), and nuclei were identified as a readout of cell counts
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