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In prostate cancer, CBP/p300-mediated histone acetylation activates autophagy pathways, which in turn suppress tumorigenic potential [193]

Severe deficiency is a cause of epilepsy: In the 1950s, an unintended experiment showed that when B6 was accidentally left out of infant formula, the babies had seizures

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Researchers also distinguish reduced glutathione (GSH) from the disulfide GSSG, since it is the GSSG/2GSH ratio, not total glutathione, that Schafer and Buettner (Free Radical Biology and Medicine, 2001) established as the quantitative index of the cellular redox environment