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Acetaminophen and oral progesterone share similar absorption windows, making this a reasonable pharmacokinetic proxy
The simulation time-span was extended to 20 hours in order to discern what exposure time and concentration would yield a 70% of normal reduction of GSH
Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ
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Gehrig SM, van der Poel C, Hoeflich A, et al
Nrf2 also regulates the expression of genes that control inflammatory and immune system responses (Kasprzak et al., 2020)
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