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In a second cohort that was given polyclonal IgG from vaccinated macaques or control animals, loss of TGF- and increased IL-6 production by activated pulmonary macrophages was observed in macaques that were pre-treated with anti-S IgG, and lung pathology was described as skewed towards immunopathological inflammation

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Peluso, G

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Tirzepatide carries a similar gastrointestinal side effect profile to semaglutide, though some patients report milder nausea

Eur J Pharmacol 218 : 117121 Hurd Y, Ungerstedt U