The most accurate framing is that the gut-skin connection is real, the research base is growing, and the best products are the ones that respect that complexity rather than oversimplify it
While it does not cure PEM, it may help raise the threshold at which a crash is triggered, providing patients with a slightly larger, more forgiving energy envelope
AirID In 2020, Kido et al
Avoid use unless specifically recommended by your clinician
Concentration-wise, this ingredient is rarely used pure and usually shows up as part of a standardized centella extract where reported content ranges from 0.02-3.06%
When mitochondria work well, the body maintains stable energy, clear thinking, and calm mood regulation