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The long-term effects and safety of these natural boosters are still being researched

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Elevated levels of the IGF-1 LR3 tracer were observed in tissues such as kidneys, ovaries, and adrenal glands in murine models

doi:10.1016/S0969-2126(02)00933-4 ^ Kabashima T., Kawaguchi T., Wadzinski B.E., Uyeda K

So a common-sense argument is that if these variants were impacting adverse events from vaccines, that would clearly be seen in the data