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Liraglutide induced a significant improvement in mechanical allodynia over time compared with the vehicle-treated group (day 14: liraglutide 20 g p = 0.0098, day 28: liraglutide 20 g p = 0.0038, dexamethasone 20 g p = 0.0002, compared to vehicle-treated group)

5.2 Patient selection should be driven by complication burden, not BMI alone This shift has important implications for patient selection

The effects of carvedilol on various K+ channels, including Kv, KAch, KATP and K2P, may have a positive effect on glucose homeostasis, contributing to clinical efficacy in the treatment of patients with hypertension and type 2 diabetes (Li, 2022)