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It works by signaling cells to rebuild collagen and calm inflammation, influencing the activity of roughly 4,000 genes tied to repair

Nrf2 expression by neurons, astroglia, and microglia in the cerebral cortical penumbra of ischemic rats

The widespread chronic pain experienced by FM patients may be linked to serotonin's role in muscle function and skeletal muscle fiber growth (Chandran et al., 2012)

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This review further discusses the current understanding of genetic etiologies and altered physiology leading to disease, such as neuroinflammation, integrated stress response, aberrant proteostasis and mitochondrial dysfunction, among others

However, oral forms are limited by reduced absorption and the need for higher doses, which may lead to inconsistent results