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The protocol is individualized, supervised, and built around your clinical baseline, not a generic dosing guide

Erol & Karpyak, Drug and Alcohol Dependence (2015)

doi: 10.3389/fpsyt.2025.1589663 Received 10 March 2025 Accepted 06 May 2025 Published 29 May 2025 Volume 16 - 2025 Edited by Paulo Santos, University of Porto, Portugal Reviewed by Martn Garca Juarez, Autonomous University of Nuevo Len, Mexico Gayane Vardanyan, Yerevan State Medical University, Armenia Updates Copyright 2025 Luan, Wang, Shi, Zhang, Wang, Zhou, Wu, Liu, Li, Zhang, Shao, Chen, Chu and Wei

Neither compound is FDA-approved

A deficiency of vitamins B6 and B12 has been associated with reduced brain function