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The neonatal Fc receptor: Key to homeostasiccontrol of IgG and IgG-related biopharmaceuticals

Results Neuronal GCLC knockout leads to brain atrophy accompanied by neuronal cell death To examine how the declines in GCLC and glutathione might affect brain homeostasis, we prepared GCLC floxed X CaMKII-Cre (GCLC-KO) mice whose GCLC expression is deleted in calcium/calmodulin-dependent protein kinase II (CaMKII)-positive neurons

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At the end of the study, final blood samples were taken, and the animals were euthanized by cardiac injection

A.StrotmeyerE