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Diabetologia 54, 30933100
Comparative metabolic and hepatic effects of GLP-1-based mono-, dual-, and triple-agonist therapies GLP-1 receptor signaling Intestinal L-cells serve as the primary source of GLP-1 synthesis, which operates via G-protein coupled receptors present in pancreatic beta cells, gastrointestinal and central neural systems, cardiac tissues, and kidneys [26]
13 Fiber also contributes significantly to feelings of fullness and satiety, complementing the medication's effects, and helps stabilize blood sugar release after meals
But there IS a lot of hype floating around this stack, and most of it comes from people who dont understand the underlying pharmacology or how to properly dose and cycle either compound
PMID 12527699
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