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Apart from DSePA, our group has also studied the radioprotective activity of another organoselenium compound, dihydroxy-1-selenolane (DHS), which was earlier reported for GPx-like activity under in vitro conditions by Iwaoka and co-workers [93, 94]
Proc Natl Acad Sci USA 105:1791317918 Di Giorgio FP, Carrasco MA, Siao MC et al (2007) Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model
In stark contrast, the marketed "Stable BPC 157" degrades more rapidly in comparable peptidase assays, consistent with its increased polarity when exposed to the small intestine's elevated pH levels
Whether that additional elimination provides additional benefit is unknown
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