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In intestinal ischaemia-reperfusion (IIR-ALI)-induced ALI, knockdown of Nrf2 exacerbated ALI injury, further reducing GPX4 expression and relative GSH content [62]
In CKD patients, alterations in the gut microbiota and metabolite wield significant consequences as metabolites generally demonstrated to promote health, chiefly short-chain fatty acids (SCFAs), are reduced
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