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doi: 10.2174/0125899775370658250713030329 94 NazerianY.GhasemiM.YassaghiY.NazerianA.HashemiS

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Adverse reactions were broadly similar to adults but with a higher incidence of gallbladder events, emphasizing the need for targeted counseling and monitoring in adolescents. ESSENCE MASH with F2F3 fibrosis ESSENCE studied adults with biopsyconfirmed MASH and F2F3 fibrosis, randomizing them to semaglutide 2.4 mg or placebo with an initial analysis at week 72 and planned continuation to week 240 for clinical outcomes