Apoptosis and glutathione: Beyond an antioxidant Wu G., et al
found that subchondral injection of bone marrow-derived MSCs is significantly more effective than intra-articular delivery in delaying total knee arthroplasty (TKA), with a 15-year randomized trial showing a 70% TKA rate in knees treated intra-articularly versus only 20% in those treated subchondrally (Hernigou et al., 2021a)
Rosenthal DI, Yom SS, Liu L, Machtay M, Algazy K, Weber RS, et al
Proc Natl Acad Sci USA.1984;81:9359
A 3D neurovascular microfluidic model consisting of neurons, astrocytes and cerebral endothelial cells as a blood-brain barrier
In conditions characterized by chronic immune dysregulation, such as autoimmunity in Long COVID, the failure of this delicate S-glutathionylation process contributes to sustained tissue damage and cellular miscommunication