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Yang et al., 2012)

Historical descriptions, proposed mechanisms, and outcomes reported in experimental models should not be interpreted as proof of clinical efficacy, established safety, or an approved medical use

The encoded protein has been identified as a moonlighting protein based on its ability to serve dual functions as a peroxidase as well as a structural protein in mature spermatozoa

Spectrum of variants in 389 Chinese probands with familial exudative vitreoretinopathy

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ScGrx7 and PfGrx both have typical ping-pong kinetics with GSSCys and GSH and cannot be saturated at infinite substrate concentrations in accordance with previous results from GSSEtOH assays on ScGrx7 (ref