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Abstract A central process contributing to the phenotype of aging is cellular senescence
Mitigation: Always dose post-workout (your muscle uptake of glucose is highest then blood glucose crash is less severe) Have fast-acting carbs nearby for the first several doses (fruit, dextrose) Never inject fasted Start at 20 mcg and assess blood glucose response before titrating Consider running a continuous glucose monitor (CGM) for the first cycle Libre or Dexcom gives you real-time data If you're already running GLP-1s (Reta, Tirz, semaglutide), add IGF-1 LR3 cautiously the appetite suppression from GLP-1s means you may not feel hunger signals that would otherwise warn you about low blood glucose
doi:10.1093/humupd/dmad004 Zhang H, Liu S, Fu S, et al
Our previous work has shown that increased levels of oxidative stress and reduced glutathione are not only present in older people, but also in people with HIV, a viral infection, and in patients with diabetes
