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To treat chronic lung disease Study results are mixed
Its activity intersects two major metabolic pathways simultaneously: the NAD+ biosynthesis pathway (by consuming nicotinamide, an NAD+ precursor, NNMT competes with the NAD+ salvage pathway) and the methyl-donor pathway (by consuming SAM, NNMT reduces the availability of methyl groups for epigenetic and metabolic methylation reactions)
2006 Apr;97(2):303-9 (2) Shustanova TA, Bondarenko TI, Milyutina NP, Mikhaleva II
The overarching principle is to err on the side of caution: the safety of this compounded medication in pregnancy has not been established, and available evidence indicates it could be highly unsafe
Therapeutically, the synthetically produced peptide BPC-157 is not currently approved for use as a human drug
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